Keftab Antibiotic Uses, Side Effects, Dosage, and Safety Tips
Jun 28, 2025
Archer Calloway
by Archer Calloway

It’s wild how a small pill like Keftab can become such a relief and yet bring out a load of questions whenever the doctor scribbles it on a prescription slip. If you've ever stared nervously at a new bottle of antibiotics, you’re not alone. When I picked up Keftab for the first time, I was suddenly hit with worries: How does this work? Will it make me feel better fast, or am I in for some nasty side effects? It turns out, Keftab is a pretty interesting player in the world of antibiotics—one worth getting to know before you pop that first dose.

What is Keftab and How Does it Work?

Keftab isn’t just a fancy name pulled from a word jumble. It’s actually the brand name for cephalexin, a type of antibiotic that’s been handled in clinics and pharmacies since 1967. Its main job? To slam the brakes on certain bacteria that cause everything from sinus infections to skin abscesses. The way Keftab works is clever: it keeps bacteria from building their protective cell wall, which makes the bugs rupture and die. That’s a pretty brutal—but effective—way to stop an infection.

Doctors reach for Keftab when the infection is likely due to Gram-positive bacteria, like Streptococcus or Staphylococcus. It’s also used to battle some Gram-negative bacteria (that’s doctor speak for the tougher crowd). You’ll most likely find this pill prescribed for:

  • Strep throat and other throat infections
  • Ear infections (especially in kids who seem to pick them up like souvenirs from school)
  • Bone and joint infections (osteomyelitis or even, in some rare cases, for dental work)
  • Urinary tract infections—especially when the patient can’t handle the go-to antibiotics
  • Simple skin infections, including boils and cellulitis

It’s taken by mouth—usually as a capsule or tablet, sometimes as a liquid for little ones or adults who hate swallowing pills. The way your body deals with Keftab is also pretty efficient. Your gut absorbs it quickly, it zips around in your blood, and is out of your system (via urine) in about 6-12 hours. That quick turnover is good because it means you need to keep up with regular doses—typically every 6-12 hours, depending on what your doctor says. Keftab doesn't mess with viruses, so if you’re battling the flu, this drug won’t help at all.

Here’s a quick peek at some hard facts about Keftab from clinical references:

AspectDetails
Active IngredientCephalexin
Introduced1967
Usual Adult Dose250-500mg every 6 hours
Common UsesThroat, skin, ears, UTI
Side EffectsUpset stomach, nausea, diarrhea
Pregnancy CategoryB (relatively safe)

Most people start to feel a change by the second or third day, but it’s critical not to quit your prescription early. Cut your treatment short, and you’re setting up those sneaky bacteria for a comeback—and this time, they might come back tougher.

Who Should (and Shouldn't) Use Keftab?

You know that ad where they say, “Not for everyone”? Well, that 100% applies to Keftab. Some folks get a red light right away. For example, anyone with a severe allergy to cephalosporins or penicillins should steer clear. Cross-reactions don’t happen to everyone, but when they do, you’ll know it—think rash, swelling, and sometimes trouble breathing (not fun, trust me; a friend of mine ended up in the ER over this exact issue years ago).

Kidney disease is another caution flag, since Keftab relies on your kidneys to flush it out. If your filters are working slow, the drug piles up and can cause more side effects. Pregnant people can generally use Keftab since studies haven’t shown birth defects or major risks. It’s classified as Category B, meaning animal studies looked good, and there’s no bad news in human studies so far. But, always talk to your OB-GYN, since everyone’s body (and baby) is different.

Elderly folks might process the drug a bit slower. I remember my dad’s doctor double-checking his kidney function before writing a script. Pediatricians also love Keftab for ear and throat infections, but dosing is super weight-specific—never eyeball it at home.

Adults, kids, dogs—yep, even vets reach for cephalexin. My neighbor’s bulldog, Daisy, cruised through a nasty paw infection thanks to her twice-daily Keftab routine. The medication, though, isn’t a cure-all. It won’t touch viral infections and shouldn’t be used if you aren’t sure what’s causing your symptoms. That’s how resistance gets worse, and nobody wants to arm already tough bacteria with more tricks.

Common Side Effects and How to Handle Them

Common Side Effects and How to Handle Them

No one likes to hear the side effect list rattled off, but it’s better to be ready than blindsided. Keftab is considered well-tolerated, but it can still trigger some stomach drama. Expect nausea, mild diarrhea, or a general queasiness about an hour after you take a dose. Not surprising, since antibiotics often wipe out both the bad and good bacteria in your gut.

Here’s a tip I picked up from a pharmacist friend: take Keftab with a small meal instead of on an empty stomach. Keeps the nausea at bay for most people. Drinking a full glass of water with each dose helps too. Probiotics—either from yogurt, kefir, or supplement—sometimes keep your gut happier during treatment, although that science is still up for debate.

Some side effects need a call to your doctor ASAP:

  • Severe watery or bloody diarrhea (could be C. diff infection, which needs different meds)
  • Fever, rash, or swelling—potential signs of an allergic reaction
  • Unusual tiredness, bruising, or yellowing skin (these sound rare, but mention them regardless)

Most people never see these rare symptoms, but it’s good to know about them. And like with most antibiotics, women can develop a yeast infection after a Keftab course because the drug sometimes wipes out friendly protective bacteria. Fast remedy? Over-the-counter antifungal meds usually fix the issue; but if symptoms stick around, check in with your doctor.

I always remind folks not to double up on doses if you forget one—just take it as soon as you remember, unless it’s already close to your next dose. Then skip it. Piling on more pills just gives you a higher chance of side effects without better results.

As Dr. Eileen M. Dunne noted in a 2022 CDC interview:

“People often forget that antibiotics, even the milder ones like Keftab, have real risks. The best treatment is the shortest, safest prescription necessary.”

She’s right. Taking more than you need or using antibiotics too often simply trains bacteria to get smarter and harder to treat. That’s literally the root of the antibiotic resistance crisis we're all hearing about.

Troubleshooting: Questions, Tips, and Myths About Keftab

I get a bunch of quick-fire questions whenever someone I know starts a course of Keftab, so let’s clear the air on a few classics:

  • "Can I drink with Keftab?" – You might have heard antibiotics and booze don’t mix. Technically, Keftab doesn’t have a direct clash with alcohol, but heavy drinking can slow down your recovery and irritate your gut even more, so it’s smart to avoid it until you finish your meds.
  • "How long before I feel better?" – Most people see improvements within a couple of days. But don’t quit before your prescription is gone—even if you feel totally fine. Stopping early gives the bacteria a second chance.
  • "Should I stop if I get a rash?" – Yes, and call your doctor. Rashes can be mild, but sometimes they’re your body waving a red flag that things aren’t okay.
  • "Can I share leftover Keftab with a sick friend?" – Absolutely not! The infection might be viral or need a different antibiotic, and sharing can feed resistance or trigger allergies in someone else.
  • "Does Keftab mess with birth control?" – Unlike rifampin, Keftab (cephalexin) doesn’t decrease birth control pill effectiveness in most cases. Still, if you have tummy trouble and throw up, your pills might not work as well, so use backup for the week.

If there’s one tip to highlight, it’s to take your Keftab at the same times every day. Set a reminder. Consistency means steadier drug levels, which equals better infection fighting.

I’ll also point out that you should always check with your health provider before starting or stopping any meds—yes, even if it's "just" an antibiotic prescribed in the past. Resistance is a huge problem; don't play into it by self-medicating.

What to Expect: Day by Day on Keftab

What to Expect: Day by Day on Keftab

The first day on Keftab usually doesn’t feel much different than before you started—except you might psych yourself up to notice every twinge in your tummy! By day two or three, if the antibiotic is the right match, pain and weird symptoms should ease up. Swelling, redness, or fever generally drop off too if it was a skin infection. For strep throat, the most annoying puzzle piece is soreness that can persist; lozenges and warm drinks help while the Keftab gets to work.

Don’t panic if you’re not 100% better within 24 hours. Everyone’s different, and some infections hang around stubbornly. If you reach day five with no improvement—or symptoms get worse—call your doctor. They might want to switch medications or check for other issues (like, is it actually viral?).

I keep Keftab in my mental "reliable but respect-required" medicine cabinet. I've watched it work wonders—whether it's Elenor’s relentless UTI that just wouldn't quit until she tried Keftab, or my nephew’s impromptu wrestling injury turned red and angry. But these wins happened because we never skipped doses or cut corners with timing. That’s really the key to getting the most out of any antibiotic.

Track your body for side effects, let your doctor know if anything feels off, and never share your prescription. Remember, antibiotics can heal, but they also need us to play by the rules.