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Tag: narrow therapeutic index
Digoxin Generics: Why Bioavailability and Monitoring Matter More Than You Think
Digoxin generics may be bioequivalent on paper, but small differences in absorption can cause toxicity or treatment failure-especially in older adults. Learn why monitoring and sticking to one brand matter.
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FDA Bioequivalence Standards for NTI Drugs: What You Need to Know
The FDA enforces stricter bioequivalence rules for narrow therapeutic index (NTI) drugs like warfarin and digoxin, requiring tighter limits and special testing to ensure safety. Learn how these standards protect patients and what you need to know if you take one.
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NTI Drug List: Common Medications with Narrow Therapeutic Windows
NTI drugs have a tiny margin between effective and toxic doses. Common examples include warfarin, lithium, digoxin, phenytoin, and tacrolimus. These require strict monitoring and careful dosing to avoid serious harm.
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